Twenty-four-year-old Kara Zor-El, who was taken in by the Danvers family when she was 13 after being sent away from Krypton, must learn to embrace her powers after previously hiding them. The Danvers teach her to be careful with her powers, until she has to reveal them during an unexpected disaster, setting her on her journey of heroism.
Melissa Benoist
as Kara Danvers / Supergirl / Kara Zor-El
Chyler Leigh
as Alex Danvers / Sentinel
David Harewood
as J'onn J'onzz / Martian Manhunter
Katie McGrath
as Lena Luthor
Jesse Rath
as Querl 'Brainy' Dox / Brainiac-5
Nicole Maines
as Nia Nal / Dreamer
Azie Tesfai
as Kelly Olsen / Guardian
Julie Gonzalo
as Andrea Rojas / Acrata
Staz Nair
as William Dey
Peta Sergeant
as Nyxlygsptlnz / 'Nyxly'