Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.
Eric McCormack
as Will Truman
Debra Messing
as Grace Adler
Sean Hayes
as Jack McFarland
Megan Mullally
as Karen Walker