After the death of his wife, Danny enlists his best friend and his brother-in-law to help raise his three daughters, D.J., Stephanie, and Michelle.
John Stamos
as Jesse Katsopolis
Bob Saget
as Danny Tanner
Dave Coulier
as Joey Gladstone
Candace Cameron Bure
as D.J. Tanner
Jodie Sweetin
as Stephanie Tanner
Lori Loughlin
as Rebecca Katsopolis
Blake Tuomy-Wilhoit
as Nicky Katsopolis
Dylan Tuomy-Wilhoit
as Alex Katsopolis
Mary-Kate Olsen
as Michelle Tanner
Andrea Barber
as Kimmy Gibbler
Ashley Olsen
as Michelle Tanner