In Tree Hill, North Carolina two half brothers share a last name and nothing else. Brooding, blue-collar Lucas is a talented street-side basketball player, but his skills are appreciated only by his friends at the river court. Popular, affluent Nathan basks in the hero-worship of the town, as the star of his high school team. And both boys are the son of former college ball player Dan Scott whose long ago choice to abandon Lucas and his mother Karen, will haunt him long into his life with wife Deb and their son Nathan.
James Lafferty
as Nathan Scott
Bethany Joy Lenz
as Haley James Scott
Sophia Bush
as Brooke Davis
Austin Nichols
as Julian Baker
Robert Buckley
as Clay Evans
Shantel VanSanten
as Quinn James
Jackson Brundage
as Jamie Scott
Lee Norris
as Marvin 'Mouth' McFadden
Lisa Goldstein Kirsch
as Millicent Huxtable
Stephen Colletti
as Chase Adams
Tyler Hilton
as Chris Keller
Paul Johansson
as Dan Scott