Physicists Leonard and Sheldon find their nerd-centric social circle with pals Howard and Raj expanding when aspiring actress Penny moves in next door.
Johnny Galecki
as Leonard Hofstadter
Jim Parsons
as Sheldon Cooper
Kaley Cuoco
as Penny
Simon Helberg
as Howard Wolowitz
Kunal Nayyar
as Rajesh Koothrappali
Melissa Rauch
as Bernadette Rostenkowski
Mayim Bialik
as Amy Farrah Fowler