As a child living in Africa, Jill Young saw her mother killed while protecting wild gorillas from poachers led by Andrei Strasser. Now an adult, Jill cares for an orphaned gorilla named Joe -- who, due to a genetic anomaly, is 15 feet tall. When Gregg O'Hara arrives from California and sees the animal, he convinces Jill that Joe would be safest at his wildlife refuge. But Strasser follows them to the U.S., intent on capturing Joe for himself.
Charlize Theron
as Jill Young
Bill Paxton
as Gregg O'Hara
Rade Šerbedžija
as Strasser
Peter Firth
as Garth
David Paymer
as Harry Ruben
Regina King
as Cecily Banks
Robert Wisdom
as Kweli
Naveen Andrews
as Pindi
Lawrence Pressman
as Dr. Baker
Linda Purl
as Dr. Ruth Young
Mika Boorem
as Young Jill Young
Geoffrey Blake
as Vern