Lincoln Rhyme was the department's top homicide detective and leading expert in criminal forensics until an injury left him paralyzed, depressed, and incapable of working. But when a gruesome murder in Manhattan leaves detectives baffled, they call on Rhyme to help solve the mystery. Amelia Donaghy, a rookie cop whose quick thinking preserved a gruesome murder scene, is enlisted by Rhyme to be his on-the-scene forensics expert. With Amelia reluctantly acting as Rhyme's able-bodied go-between, the pair piece together cryptic clues the killer leaves behind at the scene of the crime, hoping to catch the grisly serial killer.
Denzel Washington
as Lincoln Rhyme
Angelina Jolie
as Amelia Donaghy
Queen Latifah
as Thelma
Michael Rooker
as Captain Howard Cheney
Michael McGlone
as Detective Kenny Solomon
Luis Guzmán
as Eddie Ortiz
Leland Orser
as Richard Thompson
John Benjamin Hickey
as Dr. Barry Lehman
Bobby Cannavale
as Steve, Amelia's Boyfriend
Ed O'Neill
as Detective Paulie Sellitto
Richard Zeman
as Lieutenant Carl Hanson
Olivia Birkelund
as Lindsay Rubin
