When Papa Smurf is mysteriously taken by evil wizards, Razamel and Gargamel, Smurfette leads the Smurfs on a mission into the real world to save him. With the help of new friends, the Smurfs must discover what defines their destiny to save the universe.
Rihanna
as Smurfette (voice)
James Corden
as No Name (voice)
Nick Offerman
as Ken (voice)
JP Karliak
as Gargamel / Razamel (voice)
Dan Levy
as Joel (voice)
Amy Sedaris
as Jaunty (voice)
Natasha Lyonne
as Mama Poot (voice)
Sandra Oh
as Moxie Smurf (voice)
Jimmy Kimmel
as Tardigrade (voice)
Octavia Spencer
as Asmodius (voice)
Nick Kroll
as Chernobog (voice)
Hannah Waddingham
as Jezebeth (voice)