Gru is recruited by the Anti-Villain League to help deal with a powerful new super criminal.
Steve Carell
as Gru (voice)
Kristen Wiig
as Lucy (voice)
Benjamin Bratt
as Eduardo/El Macho (voice)
Miranda Cosgrove
as Margo (voice)
Russell Brand
as Dr. Nefario (voice)
Ken Jeong
as Floyd (voice)
Steve Coogan
as Silas (voice)
Elsie Fisher
as Agnes (voice)
Dana Gaier
as Edith (voice)
Moisés Arias
as Antonio (voice)
Nasim Pedrad
as Jillian (voice)
Kristen Schaal
as Shannon (voice)