All the passengers on an airplane headed for San Francisco are drugged, and when they wake up, it is discovered that a quarter-million dollars is missing. Charlie Chan--and, of course, his #1 son--must discover the identity of the person who doped the passengers and stole the money.
Roland Winters
as Charlie Chan
Keye Luke
as Lee Chan
Mantan Moreland
as Birmingham Brown
Noel Neill
as Jane Marshall
Tim Ryan
as Lt. Mike Ruark
Iris Adrian
as Wanda LaFern
Elena Verdugo
as Connie Jackson
Milburn Stone
as Pilot Tim Norton
Paul Maxey
as John Anderson
Joel Marston
as Co-Pilot Don Blake
Lyle Talbot
as Andrew J. Barrett
John Eldredge
as W. E. French
