The mega-corporate Daedalus Group is under attack by a small group of activists known as the Ghost of Icarus. While taking care of some of the victims of the bombing, Black Jack encounters Dr. Kiriko, also known as Death Incarnate, who just like him, asks his patients huge sums of money but instead of saving them, he offers them a painless death. When the activist group requests both doctors’ collaboration, Black Jack finds himself caught in a spiral of life, death and treason while trying to save his patients' lives and avoid the breaking of a biological war that could destroy humanity.
大塚明夫
as Black Jack (voice)
水谷優子
as Pinoko (voice)
石井真
as Largo (voice)
内海賢二
as Inspector Tomobiki (voice)
平山あや
as Midori (voice)
石垣佑磨
as Rock (voice)
鹿賀丈史
as Kiriko (voice)
川瀬晶子
as Kumiko Honma (voice)
富田耕生
as Master (voice)
江川央生
as Doubling (voice)
笹沼晃
as Pick (voice)
兵藤まこ
as Black Jack's mother (voice)