When a deadly airborne virus threatens to wipe out the northeastern United States, teacher Elliot Moore and his wife Alma flee from contaminated cities into the countryside in a fight to discover the truth. Is it terrorism, the accidental release of some toxic military bio weapon -- or something even more sinister?
Mark Wahlberg
as Elliot Moore
Zooey Deschanel
as Alma Moore
John Leguizamo
as Julian
Ashlyn Sanchez
as Jess
Betty Buckley
as Mrs. Jones
Spencer Breslin
as Josh
Robert Bailey Jr.
as Jared
Frank Collison
as Nursery Owner
Jeremy Strong
as Private Auster
Alan Ruck
as Principal
Victoria Clark
as Nursery Owner's Wife
M. Night Shyamalan
as Joey (voice)