Dispatched from his basement room on an errand for his mother, slacker Jeff might discover his destiny (finally) when he spends the day with his brother as he tracks his possibly adulterous wife.
Jason Segel
as Jeff Thompkins
Ed Helms
as Pat Thompkins
Susan Sarandon
as Sharon Thompkins
Judy Greer
as Linda Thompkins
Rae Dawn Chong
as Carol
Steve Zissis
as Steve
Evan Ross
as Kevin
Matt Malloy
as Barry
Benjamin Brant Bickham
as TV Pitchman
Lee Nguyen
as Clerk
Tim J. Smith
as Guard
Ernest James
as Guard
