In the year 2024, the ozone layer is believed to have been destroyed, and it's up to MacLeod and Ramirez to set things right. Opposition comes from both the planet Ziest (MacLeod and Ramirez's homeworld) and a corporation profiting from the supposed lack of ozone. Also, flashbacks show the story behind MacLeod and Ramirez's exile from Ziest.
Christopher Lambert
as Connor 'The Highlander' MacLeod
Sean Connery
as Juan Sanchez Villa-Lobos Ramirez
Virginia Madsen
as Louise Marcus
Michael Ironside
as Gen. Katana
John C. McGinley
as David Blake
Phillip Brock
as Cabbie
Rusty Schwimmer
as Drunk
Ed Trucco
as Jimmy
Steven Grives
as Hamlet
Jimmy Murray
as Horatio
Pete Antico
as Corda
Peter Bucossi
as Reno