The evil wizard Gargamel creates a couple of mischievous Smurf-like creatures called the Naughties that he hopes will let him harness the all-powerful, magical Smurf-essence. But when he discovers that only a real Smurf can give him what he wants, and only a secret spell that Smurfette knows can turn the Naughties into real Smurfs, Gargamel kidnaps Smurfette and brings her to Paris, where he has been winning the adoration of millions as the world¹s greatest sorcerer. It's up to Papa, Clumsy, Grouchy, and Vanity to return to our world, reunite with their human friends Patrick and Grace Winslow, and rescue her! Will Smurfette, who has always felt different from the other Smurfs, find a new connection with the Naughties Vexy and Hackus or will the Smurfs convince her that their love for her is True Blue?
Hank Azaria
as Gargamel
Neil Patrick Harris
as Patrick Winslow
Jayma Mays
as Grace Winslow
Brendan Gleeson
as Victor Doyle
Katy Perry
as Smurfette (voice)
Jacob Tremblay
as Blue Winslow
Nancy O'Dell
as Nancy O'Dell
Karim Babin
as Room Service Waiter
Gaston Morrison
as New York Taxi Driver
Jocelyn Blanchard
as Toad Man
Erika Rosenbaum
as Pregnant Mom
Carolina Bartczak
as Peanut Mom
