A deadly airborne virus finds its way into the USA and starts killing off people at an epidemic rate. Col. Sam Daniels' job is to stop the virus spreading from a small town, which must be quarantined, and to prevent an over reaction by the White House.
Dustin Hoffman
as Sam Daniels
Rene Russo
as Robby Keough
Morgan Freeman
as General Billy Ford
Kevin Spacey
as Casey Schuler
Cuba Gooding Jr.
as Major Salt
Donald Sutherland
as General Donald McClintock
Patrick Dempsey
as Jimbo Scott
Zakes Mokae
as Dr. Benjamin Iwabi
Malick Bowens
as Dr. Raswani
Susan Lee Hoffman
as Dr. Lisa Aronson
Benito Martinez
as Dr. Julio Ruiz
Bruce Jarchow
as Dr. Mascelli