Hank marries the divorced Joan, who's the mother of teens Sebastian and Jessica. After living with his new family for years, Hank announces that he's getting a sex change operation. The family deserts Hank, with Jessica going her own way and Sebastian staying with his mom. But Joan becomes an alcoholic, so Sebastian moves back in with Hank — now Henrietta — who turns out to be far more supportive than anyone else.
Adrian Grenier
as Sebastian Cole
Clark Gregg
as Hank / Henrietta
Aleksa Palladino
as Mary
Margaret Colin
as Joan Cole
John Shea
as Hartley Cole
Marni Lustig
as Jessica Cole
Joan Copeland
as Grandmother Cole
Tom Lacy
as Grandfather Cole
Gabriel Macht
as Troy
Herbert Russell
as Wayne
Greg Haberny
as Jimmy Bogardus
Peter McRobbie
as Principal
