In the year 2035, convict James Cole reluctantly volunteers to be sent back in time to discover the origin of a deadly virus that wiped out nearly all of the earth's population and forced the survivors into underground communities. But when Cole is mistakenly sent to 1990 instead of 1996, he's arrested and locked up in a mental hospital. There he meets psychiatrist Dr. Kathryn Railly, and patient Jeffrey Goines, the son of a famous virus expert, who may hold the key to the mysterious rogue group, the Army of the 12 Monkeys, thought to be responsible for unleashing the killer disease.
Bruce Willis
as James Cole
Madeleine Stowe
as Dr. Kathryn Railly
Brad Pitt
as Jeffrey Goines
Christopher Plummer
as Dr. Goines
David Morse
as Dr. Peters
Jon Seda
as Jose
Christopher Meloni
as Lt. Halperin
Joey Perillo
as Detective Franki
LisaGay Hamilton
as Teddy
Matt Ross
as Bee
Annie Golden
as Woman Cabbie
Michael Chance
as Scarface