In a world where supervillains are commonplace, two estranged childhood best friends reunite after one devises a treatment that gives them powers to protect their city.
Melissa McCarthy
as Lydia Berman
Octavia Spencer
as Emily Stanton
Jason Bateman
as The Crab
Bobby Cannavale
as The King
Pom Klementieff
as Laser
Melissa Leo
as Allie
Taylor Mosby
as Tracy
Marcella Lowery
as Grandma Norma
Melissa Ponzio
as Rachel Gonzales
Ben Falcone
as Kenny
Nate Hitpas
as Walter
Jevon White
as Robber 1
