After being bitten by a genetically altered spider at Oscorp, nerdy but endearing high school student Peter Parker is endowed with amazing powers to become the superhero known as Spider-Man.
Tobey Maguire
as Spider-Man / Peter Parker
Willem Dafoe
as Green Goblin / Norman Osborn
Kirsten Dunst
as Mary Jane Watson
James Franco
as Harry Osborn
Cliff Robertson
as Ben Parker
Rosemary Harris
as May Parker
J.K. Simmons
as J. Jonah Jameson
Joe Manganiello
as Flash Thompson
Gerry Becker
as Maximilian Fargas
Bill Nunn
as Joseph 'Robbie' Robertson
Jack Betts
as Henry Balkan
Stanley Anderson
as General Slocum