Sherlock Holmes is a master at solving the most impenetrable mysteries, but he has his work cut out for him on his latest case. As the famed detective investigates an alleged theft, he’s brought face to face with his most devious adversary yet — Professor Moriarty.
John Barrymore
as Sherlock Holmes
Roland Young
as Dr. Watson
Carol Dempster
as Alice Faulkner
Gustav von Seyffertitz
as Professor Moriarty
Louis Wolheim
as Craigin
Percy Knight
as Sid Jones
William Powell
as Forman Wells
Hedda Hopper
as Madge Larrabee
Reginald Denny
as Prince Alexis
Peggy Bayfield
as Rose Faulkner
Lumsden Hare
as Dr. Leighton
Anders Randolf
as James Larrabee
