Based on Anton Chekov's "The Three Sisters" about siblings living in a college town who struggle with the death of their father and try to reconcile relationships in their own lives.
Elizabeth Banks
as Nancy Pecket
Maria Bello
as Marcia Prior Glass
Erika Christensen
as Irene Prior
Steven Culp
as Dr. Harry Glass
Tony Goldwyn
as Vincent Antonelli
Mary Stuart Masterson
as Olga Prior
Eric McCormack
as Gary Sokol
Alessandro Nivola
as Andrew Prior
Chris O'Donnell
as David Turzin
Rip Torn
as Dr. Chebrin
