When Dr. Mike and Sully travel to Boston for Colleen's graduation from medical school, they find Dr. Mike's mother terminally ill. Sully finds himself a target for assassination by a corrupt politician.
Joe Lando
as Byron Sully
Jessica Bowman
as Colleen Cooper Cook
Shawn Toovey
as Brian Cooper
Jane Seymour
as Dr. Michaela 'Dr. Mike' Quinn
Georgann Johnson
as Elizabeth Ann Weston Quinn
Elinor Donahue
as Rebecca Quinn Dickinson
Jude Beny
as Martha
Una Kay
as Mrs. Cook
Sara McRae
as Katie Sully
