When New York architect Matt Saunders dumps his new girlfriend Jenny Johnson - a smart, sexy and reluctant superhero known as G-Girl - she uses her powers to make his life a living hell!
Uma Thurman
as Jenny Johnson
Luke Wilson
as Matt Saunders
Anna Faris
as Hannah
Eddie Izzard
as Professor Bedlam
Rainn Wilson
as Vaughn Haige
Stelio Savante
as Leo
Mike Iorio
as Lenny
Wanda Sykes
as Carla Dunkirk
Margaret Anne Florence
as Bartender
Catherine Reitman
as TV News Reporter
Tara Thompson
as Young Jenny
Angel Sing
as Asian Businessman