Isaac has seen better days. His acting career is tanking, his blind girlfriend of 10 years plans to leave him, and his own family singles him out as a constant disappointment. Even as he takes a chance on new romance, he struggles to define his place in a world that has seemingly turned against him.
Brett Gelman
as Isaac
Judy Greer
as Ramona
Michael Cera
as Alex
Gillian Jacobs
as Tracy
Jeff Garlin
as Guy Roach
Kayla Harrity
as Susan
Shiri Appleby
as Ruthie
Megan Mullally
as Simone
Robin McDonald
as Client
Nia Long
as Cleo
Jon Daly
as Toby
Hank Chen
as Lee