Beth Bradfield (Patty Duke) is a housewife with what appears to be a stable life in an American village. One day, her 24-year-old daughter Lori (Tracey Gold), who is married to Jesse Molina (Maurice Benard) and recently gave birth to his daughter Molly (Laura and Megan Jaime), unexpectedly collapses and is hospitalized. After several tests, she is diagnosed with leukemia. Her doctor (Erick Avari) reveals to Beth that Lori is in urgent need of a donor, though her rare blood type makes finding one a difficult task.
Patty Duke
as Beth Bradfield
Tracey Gold
as Lori Molina
David Ogden Stiers
as Ken Bradfield
Gabrielle Carteris
as Megan Hollander
James Brolin
as Greg Hollander
Susan Brown
as Kate Hollander
