Myron Breckinridge flies to Europe to get a sex-change operation and is transformed into the beautiful Myra. She travels to Hollywood, meets up with her rich Uncle Buck and, claiming to be Myron's widow, demands money. Instead, Buck gives Myra a job in his acting school. There, Myra meets aspiring actor Rusty and his girlfriend, Mary Ann. With Myra as catalyst, the trio begin to outrageously expand their sexual horizons.
Raquel Welch
as Myra Breckinridge
Rex Reed
as Young Man
Mae West
as Leticia Van Allen
John Huston
as Buck Loner
Farrah Fawcett
as Mary Ann Pringle
Roger C. Carmel
as Dr. Randolph Spencer Montag
Roger Herren
as Rusty Godowski
George Furth
as Charlie Flager Jr.
Calvin Lockhart
as Irving Amadeus
Jim Backus
as Doctor
John Carradine
as Surgeon
Andy Devine
as Coyote Bill