Andrew returns to his hometown for the funeral of his mother, a journey that reconnects him with past friends. The trip coincides with his decision to stop taking his powerful antidepressants. A chance meeting with Sam - a girl also suffering from various maladies - opens up the possibility of rekindling emotional attachments, confronting his psychologist father, and perhaps beginning a new life.
Zach Braff
as Andrew Largeman
Natalie Portman
as Sam
Ian Holm
as Gideon Largeman
Peter Sarsgaard
as Mark
Jean Smart
as Carol
Armando Riesco
as Jesse
Jackie Hoffman
as Aunt Sylvia Largeman
Method Man
as Diego
Alex Burns
as Dave
Ron Leibman
as Dr. Cohen
Jim Parsons
as Tim
Michael Weston
as Kenny
