In a city in South America an outbreak of bubonic plague occurs. While people try to flee and the military close the city, an idealistic doctor decides to stay and help the sick. In the ever-changing circumstances, he puts up a brave fight, being helped by others but also involving them without being able to control the situation.
William Hurt
as Doctor Bernard Rieux
Robert Duvall
as Joseph Grand
Raúl Juliá
as Cottard
Sandrine Bonnaire
as Martine Rambert
Jean-Marc Barr
as Jean Tarrou
Victoria Tennant
as Alicia Rieux
Jorge Luz
as Old Man with the cats
Atilio Veronelli
as Dr. Horacio
Francisco Cocuzza
as Miguel
Laura Palmucci
as Miguel's Wife
Norman Erlich
as Dr. Castel
Marcos Woinsky
as Doctor Grunewald
