Term-time ends at Acme Looniversity and the Tiny Toon characters look forward to a summer filled with fun. Buster and Babs Bunny turn a water fight into a white-water rafting trip through the dangerous Deep South; Plucky Duck and Hamton Pig share the most impossibly awful car journey imaginable on the way to HappyWorldLand; Fifi's blind date becomes a "skunknophobic" nightmare; and a safari park is turned upside-down by Elmyra's search for "cute little kitties to hug and squeeze".
Charlie Adler
as Buster Bunny / Usher (voice)
Tress MacNeille
as Babs Bunny / Big Boo / Babs' Mother / Emily Duff / Roseanne Barr / Barbara Walters / Arsenio Hall / Additional Voices (voice)
Joe Alaskey
as Plucky Duck / Tupelo Toad / Johnny Carson / Ed McMahon / Elmer Fudd / Additional Voices (voice)
Don Messick
as Hamton J. Pig / Radio Announcer (voice)
Jonathan Winters
as Wade Pig / Superman (voice)
Edie McClurg
as Winnie Pig (voice)
Frank Welker
as Uncle Stinky Pig / Byron Basset / Furrball / Little Beeper / Gogo Dodo / Vinnie / Mac Duff / Additional Voices (voice)
Cree Summer
as Elmyra Duff / Mary Melody / Oprah Winfrey (voice)
Sorrell Booke
as Big Daddy Boo (voice)
Rob Paulsen
as Fowlmouth / Johnny Pew / Banjo the Woodpile Possum / Mr. Hitcher / Manager / Additional Voices (voice)
Maurice LaMarche
as Dizzy Devil / David Letterman / Horatio / Theatre Voice (voice)
Gail Matthius
as Shirley the Loon / Sissy Boo (voice)