A medical examiner discovers that an innocent shooting victim in a robbery died of bubonic plague. With only 48 hours to find the killer, who is now a ticking time bomb threatening the entire city, a grisly manhunt through the seamy underworld of the New Orleans Waterfront is underway.
Richard Widmark
as Lt. Cmdr. Clinton 'Clint' Reed M.D.
Paul Douglas
as Capt. Tom Warren
Barbara Bel Geddes
as Nancy Reed
Jack Palance
as Blackie
Zero Mostel
as Raymond Fitch
Dan Riss
as Neff - Newspaper Reporter
Tommy Cook
as Vince Poldi - Younger Brother
Wilson Bourg Jr.
as Charlie - Sailor (uncredited)
Beverly C. Brown
as Dr. Mackey - Board of Health (uncredited)
Lewis Charles
as Kochak - Murder Victim (uncredited)
Herman Cottman
as Officer Scott - Police Lab (uncredited)
John David
as Fruit Salesman (uncredited)
