Rance Roden plans to kill off all the buffalo and thus cause the Indians to riot. After they destroy the US Cavalry, Rance and his gang will take over the West. Meanwhile, a Boston magazine gets wind of the buffalo slaughter and sends editor Kenneth Cabot and his associates to Casper, Wyoming to investigate.
Moe Howard
as Moe
Larry Fine
as Larry
Joe DeRita
as Curly-Joe
Adam West
as Kenneth Cabot
Nancy Kovack
as Annie Oakley
Mort Mills
as Trigger Mortis
Don Lamond
as Rance Roden
Rex Holman
as Sunstroke Kid
Emil Sitka
as Mr. Abernathy / Witch doctor / Cavalry colonel
Henry Gibson
as Charlie Horse
Murray Alper
as Chief Crazy Horse
Tiny Brauer
as Bartender