Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant transplant his brain into a corpse. The creature is tormented by a trapped soul in an alien shell and, after a visit to his wife who violently rejects his monstrous form, the creature wreaks his revenge on the perpetrator of his misery: Baron Frankenstein.
Peter Cushing
as Baron Victor Frankenstein
Veronica Carlson
as Anna Spengler
Freddie Jones
as Prof. Richter
Simon Ward
as Dr. Karl Holst
Thorley Walters
as Insp. Fritsch
Maxine Audley
as Ella Brandt
George Pravda
as Dr. Frederick Brandt
Geoffrey Bayldon
as Police Doctor
Colette O'Neil
as Mad Woman
Frank Middlemass
as Guest - Plumber
George Belbin
as Guest - Playing chess
Norman Shelley
as Guest - Smoking pipe
