Legendary undercover DEA agent Charlie Mayough has suddenly lost his nerves of steel. On the verge of a career-induced mental breakdown, and in complete fear of trigger-happy Mafia leader Fulvio Nesstra, Charlie seeks psychiatric help and finds himself relying on the support of an unstable therapy group and nurse Judy just to get through his work.
Sandra Bullock
as Judy Tipp
Liam Neeson
as Charles Mayough
Oliver Platt
as Fulvio Nesstra
José Zúñiga
as Fidel Vaillar
Michael DeLorenzo
as Estuvio Clavo
Richard Schiff
as Elliott
Mary McCormack
as Gloria Nesstra
Andrew Lauer
as Jason Cane
Myndy Crist
as Myrna
Paul Ben-Victor
as Howard
Mitch Pileggi
as Dexter Helvenshaw
Rick Peters
as Bennett