The titular medallion is a gift presented to young Nicole Elmi. Once the girl places the gift around her neck, she is possessed by the spirit of a dead child who was a murderess.
Richard Johnson
as Michael Williams
Joanna Cassidy
as Joanna Morgan
Ida Galli
as Jill Perkins
Edmund Purdom
as Doctor
Nicoletta Elmi
as Emily Williams
Lila Kedrova
as Contessa Cappelli
Riccardo Garrone
as Police Inspector
Dana Ghia
as Emily's Mother
Eleonora Morana
as Contessa's Maid
Tom Felleghy
as BBC Boss