A pathologist experiments with a deaf-mute woman who is unable to scream to prove that humans die of fright due to an organism he names The Tingler that lives within each person on the spinal cord and is suppressed only when people scream when scared.
Vincent Price
as Dr. Warren Chapin
Philip Coolidge
as Oliver 'Ollie' Higgins
Judith Evelyn
as Mrs. Martha Ryerson Higgins
Darryl Hickman
as David Morris
Pamela Lincoln
as Lucy Stevens
Patricia Cutts
as Isabel Stevens Chapin
William Castle
as Prologue Host (uncredited)
Bob Gunderson
as Ryerson - Screaming Convict (uncredited)
Dal McKennon
as Projectionist (uncredited)
Leon Alton
as Member of Silent Movie Audience (uncredited)
Gertrude Astor
as Member of Silent Movie Audience (uncredited)
Richard Barthelmess
as David Kinemon (archive footage) (uncredited)
