A man named Seligman finds a fainted wounded woman in an alley and he brings her home. She tells him that her name is Joe and that she is nymphomaniac. Joe tells her life and sexual experiences with hundreds of men since she was a young teenager while Seligman tells about his hobbies, such as fly fishing, reading about Fibonacci numbers or listening to organ music.
Charlotte Gainsbourg
as Joe
Stellan Skarsgård
as Seligman
Stacy Martin
as Young Joe
Shia LaBeouf
as Jerôme
Christian Slater
as Joe's Father
Uma Thurman
as Mrs. H
Sophie Kennedy Clark
as B
Connie Nielsen
as Joe's Mother
Ananya Berg
as Joe - 10 Years
Jens Albinus
as S
Anders Hove
as Odin
Simon Böer
as Man Uninterested
