The true story of three sisters who unite in the face of adversity when one of them is diagnosed with ALS, also known as Lou Gehrig's Disease.
Laura San Giacomo
as Jenifer Estess
Jane Kaczmarek
as Valerie Estess
Annabella Sciorra
as Meredith Estess
Jane Alexander
as Marilyn Estess
Maddie Corman
as Julianne Hoffenberg
Edie Falco
as Wheelchair Saleswoman
Donna Hanover
as Herself
Camryn Manheim
as Nurse Vandemal
Julianna Margulies
as Jenifer's Psychiatrist
Rob Morrow
as Dr. Richard Feldman
Reed Rudy
as Scotty
Cedric Smith
as Dr. Richards
