Joe Palooka is a naive young man whose father Pete was a champion boxer, but his lifestyle caused Joe's mother Mayme to leave him and to take young Joe to the country to raise him.
Jimmy Durante
as Knobby Walsh
Lupe VĂ©lez
as Nina Madero
Stuart Erwin
as Joe Palooka
Marjorie Rambeau
as Mayme Palooka
Thelma Todd
as Trixie
Robert Armstrong
as Pete Palooka
Mary Carlisle
as Anne Howe
William Cagney
as Al McSwatt
Franklyn Ardell
as Doc Wise
Tom Dugan
as Whitey
Louise Beavers
as Crystal
Fred 'Snowflake' Toones
as Smokey (as Snowflake)