A mad scientist, Dr. Aranya (Jackie Coogan), has created giant spiders in his Mexican lab in Zarpa Mesa to create a race of superwomen by injecting spiders with human pituitary growth hormones. Women develop miraculous regenerative powers, but men mutate into disfigured dwarves. Spiders grow to human size and intelligence.
Jackie Coogan
as Dr Aranya
Allan Nixon
as Dr. Tucker, camp physician
Richard Travis
as Dan Mulcahey, foreman
Lyle Talbot
as Narrator (voice)
Paula Hill
as Doreen Culbertson
Robert Knapp
as Grant Phillips
Tandra Quinn
as Tarantella
Chris-Pin Martin
as Pepe
Harmon Stevens
as Dr. Leland J. Masterson
Nico Lek
as Jan van Croft
Kelly Drake
as Lost Woman
John Robert Martin
as Frank