Famous and wealthy funnyman George Simmons doesn't give much thought to how he treats people until a doctor delivers stunning health news, forcing George to reevaluate his priorities with a little help from aspiring stand-up comic Ira.
Adam Sandler
as George Simmons
Seth Rogen
as Ira Wright
Leslie Mann
as Laura
Eric Bana
as Clarke
Jonah Hill
as Leo Koenig
Jason Schwartzman
as Mark Taylor Jackson
Aubrey Plaza
as Daisy Danby
RZA
as Chuck
Aziz Ansari
as Randy
Maude Apatow
as Mable
Iris Apatow
as Ingrid
Torsten Voges
as Dr. Lars