In California, a group of women struggle with personal problems as their paths intertwine in unexpected ways. Dr. Elaine Keener, the sole caretaker for her aging mother, turns to tarot card reader Christine for spiritual aid. Christine grapples with her own angst due to her lover's debilitating illness. Meanwhile, a bank manager deals with an unwanted pregnancy, two sisters pursue romantic interests and a housewife gets back into the dating game.
Glenn Close
as Dr. Elaine Keener (segments "This is Dr. Keener" and "Fantasies about Rebecca")
Cameron Diaz
as Carol Faber (segment "Love Waits For Kathy")
Calista Flockhart
as Christine Taylor (segments "Goodnight Lilly, Goodnight Christine" and "This is Dr. Keener")
Kathy Baker
as Rose (segments "Someone For Rose" and "Fantasies about Rebecca")
Amy Brenneman
as Detective Kathy Faber (segment "Love Waits For Kathy")
Valeria Golino
as Lilly (segment "Goodnight Lilly, Goodnight Christine")
Holly Hunter
as Rebecca Waynon (segment "Fantasies About Rebecca")
Matt Craven
as Walter (segments "Fantasies About Rebecca" and "Love Waits For Kathy")
Gregory Hines
as Robert (segment "Fantasies About Rebecca")
Miguel Sandoval
as Sam (segment "Love Waits For Kathy")
Noah Fleiss
as Jay (segment "Someone For Rose")
Danny Woodburn
as Albert (segments "Someone For Rose" and "Love Waits For Kathy")