Two doctors find their graveyard shift inundated with townspeople ravaged by sores. Among the wounded is Cherry Darling, a dancer whose leg was ripped from her body. As the invalids quickly become enraged aggressors, Cherry and her ex-boyfriend El Wray lead a team of accidental warriors into the night.
Rose McGowan
as Cherry Darling
Freddy Rodríguez
as Wray
Marley Shelton
as Dr. Dakota Block
Josh Brolin
as Dr. William Block
Jeff Fahey
as J.T. Hague
Michael Biehn
as Sheriff Hague
Bruce Willis
as Lieutenant Muldoon
Rebel Rodriguez
as Tony Block
Naveen Andrews
as Abby
Julio Oscar Mechoso
as Romey
Fergie
as Tammy Visan
Nicky Katt
as Joe