The story of the life and career of the baseball hall of famer, Lou Gehrig.
Gary Cooper
as Henry Louis 'Lou' Gehrig
Teresa Wright
as Eleanor Twitchell
Babe Ruth
as Babe Ruth
Walter Brennan
as Sam Blake
Dan Duryea
as Hank Hanneman
Elsa Janssen
as Christina 'Mom' Gehrig
Ludwig Stössel
as Henry 'Pop' Gehrig
Virginia Gilmore
as Myra Tinsley
Bill Dickey
as Bill Dickey
Ernie Adams
as Miller Huggins
Pierre Watkin
as Mr. Twitchell
Harry Harvey
as Joe McCarthy