An exploration of the United States of America's war on drugs from multiple perspectives. For the new head of the Office of National Drug Control Policy, the war becomes personal when he discovers his well-educated daughter is abusing cocaine within their comfortable suburban home. In Mexico, a flawed, but noble policeman agrees to testify against a powerful general in league with a cartel, and in San Diego, a drug kingpin's sheltered trophy wife must learn her husband's ruthless business after he is arrested, endangering her luxurious lifestyle.
Michael Douglas
as Robert Wakefield
Benicio del Toro
as Javier Rodriguez
Catherine Zeta-Jones
as Helena Ayala
Erika Christensen
as Caroline Wakefield
Don Cheadle
as Montel Gordon
Jacob Vargas
as Manolo Sanchez
Miguel Ferrer
as Eduardo Ruiz
Luis Guzmán
as Ray Castro
Topher Grace
as Seth Abrahms
Tomas Milian
as Gen. Arturo Salazar
Clifton Collins Jr.
as Francisco Flores
Amy Irving
as Barbara Wakefield