In the midst of World War II, Sherlock Holmes rescues the Swiss inventor of a new bomb-sight from the Gestapo and brings him to England, where he quickly falls into the clutches of the evil Professor Moriarty.
Basil Rathbone
as Sherlock Holmes
Nigel Bruce
as Doctor Watson
Lionel Atwill
as Professor Moriarty
William Post Jr.
as Dr. Franz Tobel
Kaaren Verne
as Charlotte Eberli
Dennis Hoey
as Inspector Lestrade
Holmes Herbert
as Sir Reginald
Mary Gordon
as Mrs. Hudson
Harry Cording
as Jack Brady (uncredited)
Harold De Becker
as Peg Leg (uncredited)
Paul Fix
as Mueller (uncredited)
Henry Victor
as Professor Frederic Hoffner (uncredited)