In 1856, slave Eliza plans to marry George with the consent of the Shelbys, her masters, but George's owner prevents the wedding. A few years later, Eliza flees with her son, Harry, after learning the Shelbys plan to hand them over to a crooked creditor to prevent foreclosure. George also escapes and goes on the run while Eliza and Harry are captured and brought back home. Mother and son are separated as George tries to find them both.
Margarita Fischer
as Eliza
James B. Lowe
as Uncle Tom
Arthur Edmund Carewe
as George Harris
George Siegmann
as Simon Legree
Eulalie Jensen
as Cassy
Mona Ray
as Topsy
Virginia Grey
as Evangeline 'Eva' St. Clare
Lassie Lou Ahern
as Little Harry
Lucien Littlefield
as Lawyer Marks
Adolph Milar
as Mr. Haley
J. Gordon Russell
as Loker
Gertrude Howard
as Aunt Chloe
