Charles, an attorney, and Helen, his devoted wife, seem to have everything – money, a beautiful mansion – the American Dream. However, as Helen prepares to celebrate their 18th wedding anniversary, her life takes an unexpected twist when she comes home to find her clothes packed up in a U-Haul van parked in the driveway. Charles is divorcing her and kicks her out. Helen moves in with her grandmother Madea, an old woman who doesn't take any lip from anyone. Madea helps Helen through these tough times by showing her what is really important in life. Helen is forced to rediscover love, life, and religion in her pursuit for happiness.
Kimberly Elise
as Helen McCarter
Steve Harris
as Charles McCarter
Tyler Perry
as Madea / Brian / Joe
Shemar Moore
as Orlando
Lisa Marcos
as Brenda
Tamara Taylor
as Debrah
Cicely Tyson
as Myrtle
Terrell Carter
as Reverend Carter
Carol Mitchell-Leon
as Mildred
Avery Knight
as BJ
Vickie Eng
as Christina
Tiffany Evans
as Tiffany