Leela becomes an outlaw when she and a group of ecologically-minded feminists attempt to save an asteroid of primitive life forms and the Violet Dwarf star from being destroyed, while Fry joins a secret society and attempts to stop a mysterious species known as the "Dark Ones" from destroying all life in the universe.
Billy West
as Philip J. Fry / Dr. Zoidberg / Prof. Hubert J. Farnsworth (voice)
Katey Sagal
as Turanga Leela (voice)
John DiMaggio
as Bender (voice)
Tress MacNeille
as Fanny / Michael's Wife / Boobs Vanderbilt / Dixie / Linda / Petunia / Ruth Ginsberg's Head / Mom (voice)
Maurice LaMarche
as Kif Kroker (voice)
Phil LaMarr
as Hermes Conrad (voice)
Lauren Tom
as Amy Wong (voice)
David Herman
as The Number 9 Man / Scruffy / Michael / Neputnian (voice)
Dawnn Lewis
as LaBarbara Conrad / Womens' Prison Warden (voice)
Snoop Dogg
as Snoop Dogg's Head (voice)
Phil Hendrie
as Frida Waterfall / Hutch Waterfall / The Encyclopod (voice)
Seth MacFarlane
as Mars Vegas Singer (singing voice)