Described as a reboot that will return to the franchise's suspense/horror roots and be more faithful to the spirit of the early games, capturing the “moment that comes in every Resident Evil game where you find yourself standing in the mouth of a dark passageway with one shot left in the gun, and you know something horrible is waiting for you in that darkness – that awful moment where you have to will yourself forward.” The film will “follow one central protagonist from point A to point B, as they descend deeper into hell.”
